Platelet Distribution Width (CV)
Learn about Platelet Distribution Width (CV) for clotting function variability assessment. Track blood health markers effectively.
What is Platelet Distribution Width (CV)?
Platelet Distribution Width (CV) measures the coefficient of variation in platelet size, expressed as 10 times the geometric standard deviation (10×GSD). This parameter quantifies how much individual platelet sizes vary from the average, providing detailed information about platelet heterogeneity and production quality.
Why is it Tested?
Doctors order PDW-CV as part of a complete blood count to evaluate platelet production abnormalities, assess bone marrow disorders, and investigate bleeding or clotting problems. This measurement helps characterize platelet population characteristics and guides diagnosis of platelet-related disorders.
Normal Ranges
Reference ranges vary by lab and analyzer type. Generally:
- Adults: Varies by methodology (consult lab-specific ranges)
Normal PDW-CV values indicate relatively uniform platelet sizes, reflecting steady-state platelet production and normal bone marrow function.
Reference ranges vary by authority. Track yours across multiple standards with automatic unit conversions in LabsVault.
What do Abnormal Results Mean?
Abnormal results are not a diagnosis. Always discuss your results with a qualified healthcare provider before making any medical decisions.
Low PDW-CV
Lower values indicate more uniform platelet sizes and may occur with:
- Steady-state platelet production
- Certain inherited platelet disorders
- Stable bone marrow function
High PDW-CV
Elevated values indicate greater platelet size variation and may suggest:
- Active thrombopoiesis (platelet production)
- Immune thrombocytopenic purpura (ITP)
- Myelodysplastic syndromes
- Drug-induced thrombocytopenia
- Recovery from bone marrow suppression
- Myeloproliferative disorders
How to Track Over Time
Tracking PDW-CV provides insight into bone marrow recovery and platelet production dynamics. Rising values may indicate regenerative responses to platelet destruction or consumption, while stable values suggest steady platelet production. Changes help monitor treatment effectiveness in platelet disorders.
Track your Platelet Distribution Width (CV) results over time
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