HbA1c (IFCC) (A1C-IFCC)

What is HbA1c (IFCC)?

HbA1c (IFCC) is hemoglobin A1c reported in the International Federation of Clinical Chemistry (IFCC) units of mmol/mol. It measures the percentage of hemoglobin that has glucose attached to it, reflecting average blood sugar levels over the previous 2-3 months. This standardized measurement provides consistent results across different laboratories worldwide.

Why is it Tested?

Doctors order HbA1c to diagnose diabetes, monitor long-term glucose control in diabetic patients, and assess diabetes treatment effectiveness. The IFCC standardization ensures consistent results globally, making it easier to compare values across different healthcare systems and research studies.

Normal Ranges

Reference ranges vary by lab and clinical context. General adult guidelines (IFCC units):

Normal: <42 mmol/mol
Prediabetes: 42–47 mmol/mol
Diabetes: ≥48 mmol/mol

Reference ranges vary by authority. Track yours across multiple standards with automatic unit conversions in LabsVault.

What do Abnormal Results Mean?

Abnormal results are not a diagnosis. Always discuss your results with a qualified healthcare provider before making any medical decisions.

Low HbA1c

Very low levels may indicate:

Hypoglycemia or overtreatment of diabetes
Anemia or blood disorders
Recent blood transfusions
Certain genetic hemoglobin variants

High HbA1c

Elevated HbA1c indicates poor glucose control over the past 2-3 months and may point to:

Undiagnosed diabetes
Poorly controlled diabetes
Medication non-compliance
Stress, illness, or steroid use

How to Track Over Time

HbA1c tracking provides long-term glucose control trends that daily blood sugars can’t capture. Changes typically become apparent after 6-8 weeks, making it ideal for assessing the effectiveness of treatment modifications. Consistent monitoring helps prevent diabetes complications through better glucose management.

HbA1c (IFCC)